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Transverse sinus injections drive robust whole-brain expression of transgenes

Convenient, efficient and fast whole-brain delivery of transgenes presents a persistent experimental challenge in neuroscience. Recent advances demonstrate whole-brain gene delivery by retro-orbital injection of virus, but slow and sparse expression and the large injection volumes required make this...

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Detalles Bibliográficos
Autores principales: Hamodi, Ali S, Martinez Sabino, Aude, Fitzgerald, N Dalton, Moschou, Dionysia, Crair, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266618/
https://www.ncbi.nlm.nih.gov/pubmed/32420870
http://dx.doi.org/10.7554/eLife.53639