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TANGO1 membrane helices create a lipid diffusion barrier at curved membranes

We have previously shown TANGO1 organises membranes at the interface of the endoplasmic reticulum (ER) and ERGIC/Golgi (Raote et al., 2018). TANGO1 corrals retrograde membranes at ER exit sites to create an export conduit. Here the retrograde membrane is, in itself, an anterograde carrier. This mode...

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Detalles Bibliográficos
Autores principales: Raote, Ishier, Ernst, Andreas M, Campelo, Felix, Rothman, James E, Pincet, Frederic, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266638/
https://www.ncbi.nlm.nih.gov/pubmed/32452385
http://dx.doi.org/10.7554/eLife.57822