Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons

Good’s buffers are commonly used for cell culture and, although developed to have minimal to no biological impact, they cause alterations in cellular processes such as autophagy and lysosomal enzyme activity. Using Chinese hamster ovary cells and induced pluripotent stem cell-derived neurons, this s...

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Detalles Bibliográficos
Autores principales: Cook, Sophie R., Badell-Grau, Rafael A., Kirkham, Emily D., Jones, Kimberley M., Kelly, Brendan P., Winston, Jincy, Waller-Evans, Helen, Allen, Nicholas D., Lloyd-Evans, Emyr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266671/
https://www.ncbi.nlm.nih.gov/pubmed/32490352
http://dx.doi.org/10.12688/amrcopenres.12903.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266671/
https://www.ncbi.nlm.nih.gov/pubmed/32490352
http://dx.doi.org/10.12688/amrcopenres.12903.1

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