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Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons
Good’s buffers are commonly used for cell culture and, although developed to have minimal to no biological impact, they cause alterations in cellular processes such as autophagy and lysosomal enzyme activity. Using Chinese hamster ovary cells and induced pluripotent stem cell-derived neurons, this s...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266671/ https://www.ncbi.nlm.nih.gov/pubmed/32490352 http://dx.doi.org/10.12688/amrcopenres.12903.1 |