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Bone marrow niche-derived extracellular matrix-degrading enzymes influence the progression of B-cell acute lymphoblastic leukemia

Specific and reciprocal interactions with the bone marrow microenvironment (BMM) govern the course of hematological malignancies. Matrix metalloproteinase-9 (MMP-9), secreted by leukemia cells, facilitates tumor progression via remodeling of the extracellular matrix (ECM) of the BMM. Hypothesizing t...

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Detalles Bibliográficos
Autores principales: Verma, Divij, Zanetti, Costanza, Godavarthy, Parimala Sonika, Kumar, Rahul, Minciacchi, Valentina R., Pfeiffer, Jakob, Metzler, Markus, Lefort, Sylvain, Maguer-Satta, Véronique, Nicolini, Franck E., Burroni, Barbara, Fontenay, Michaela, Krause, Daniela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266746/
https://www.ncbi.nlm.nih.gov/pubmed/31919471
http://dx.doi.org/10.1038/s41375-019-0674-7