PD-L1 Inhibitor Regulates the miR-33a-5p/PTEN Signaling Pathway and Can Be Targeted to Sensitize Glioblastomas to Radiation

Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Ionizing radiation (IR) is a standard treatment for GBM patients and results in DNA damage. However, the clinical efficacy of IR is limited due to therapeutic resistance. The programmed death ligand 1 (PD-L1) blockade has a show...

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Detalles Bibliográficos
Autores principales: Xia, Wenzheng, Zhu, Jin, Tang, Yinda, Wang, Xueyi, Wei, Xiangyu, Zheng, Xuan, Hou, Meng, Li, Shiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266984/
https://www.ncbi.nlm.nih.gov/pubmed/32537433
http://dx.doi.org/10.3389/fonc.2020.00821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266984/
https://www.ncbi.nlm.nih.gov/pubmed/32537433
http://dx.doi.org/10.3389/fonc.2020.00821

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