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Inhibition of the STAT3 Signaling Pathway Contributes to the Anti-Melanoma Activities of Shikonin

BACKGROUND: Malignant melanoma is an extremely aggressive and metastatic cancer, and highly resistant to conventional therapies. Signal transducer and activator of transcription 3 (STAT3) signaling promotes melanoma development and progression, which has been validated as an effective target in mela...

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Detalles Bibliográficos
Autores principales: Cao, Hui-Hui, Liu, Dong-Yi, Lai, Ye-Cai, Chen, Yu-Yao, Yu, Lin-Zhong, Shao, Meng, Liu, Jun-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267064/
https://www.ncbi.nlm.nih.gov/pubmed/32536866
http://dx.doi.org/10.3389/fphar.2020.00748