Prevention of Chromatin Destabilization by FACT Is Crucial for Malignant Transformation

Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not normal cells, and its expression levels correlate with poor prognosis in patients with cancer. FACT binds several components of nucleosomes and has been viewed as a factor destabilizing nucleosomes to...

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Detalles Bibliográficos
Autores principales: Sandlesh, Poorva, Safina, Alfiya, Goswami, Imon, Prendergust, Laura, Rosario, Spenser, Gomez, Eduardo C., Wang, Jianmin, Gurova, Katerina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267732/
https://www.ncbi.nlm.nih.gov/pubmed/32498018
http://dx.doi.org/10.1016/j.isci.2020.101177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267732/
https://www.ncbi.nlm.nih.gov/pubmed/32498018
http://dx.doi.org/10.1016/j.isci.2020.101177

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