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Prevention of Chromatin Destabilization by FACT Is Crucial for Malignant Transformation
Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not normal cells, and its expression levels correlate with poor prognosis in patients with cancer. FACT binds several components of nucleosomes and has been viewed as a factor destabilizing nucleosomes to...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267732/ https://www.ncbi.nlm.nih.gov/pubmed/32498018 http://dx.doi.org/10.1016/j.isci.2020.101177 |