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tugHall: a simulator of cancer-cell evolution based on the hallmarks of cancer and tumor-related genes
SUMMARY: The flood of recent cancer genomic data requires a coherent model that can sort out the findings to systematically explain clonal evolution and the resultant intra-tumor heterogeneity (ITH). Here, we present a new mathematical model designed to computationally simulate the evolution of canc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267821/ https://www.ncbi.nlm.nih.gov/pubmed/32170925 http://dx.doi.org/10.1093/bioinformatics/btaa182 |