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tugHall: a simulator of cancer-cell evolution based on the hallmarks of cancer and tumor-related genes

SUMMARY: The flood of recent cancer genomic data requires a coherent model that can sort out the findings to systematically explain clonal evolution and the resultant intra-tumor heterogeneity (ITH). Here, we present a new mathematical model designed to computationally simulate the evolution of canc...

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Detalles Bibliográficos
Autores principales: Nagornov, Iurii S, Kato, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267821/
https://www.ncbi.nlm.nih.gov/pubmed/32170925
http://dx.doi.org/10.1093/bioinformatics/btaa182