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Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions

Seizure incidence is increased in Alzheimer’s disease (AD) patients and mouse models, and treatment with the antiseizure drug levetiracetam improves cognition. We reported that one mechanism by which seizures can exert persistent effects on cognition is through accumulation of ΔFosB, a transcription...

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Detalles Bibliográficos
Autores principales: Stephens, Gabriel S., Fu, Chia-Hsuan, St. Romain, Corey P., Zheng, Yi, Botterill, Justin J., Scharfman, Helen E., Liu, Yin, Chin, Jeannie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268090/
https://www.ncbi.nlm.nih.gov/pubmed/32536852
http://dx.doi.org/10.3389/fnins.2020.00472