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Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions
Seizure incidence is increased in Alzheimer’s disease (AD) patients and mouse models, and treatment with the antiseizure drug levetiracetam improves cognition. We reported that one mechanism by which seizures can exert persistent effects on cognition is through accumulation of ΔFosB, a transcription...
Autores principales: | Stephens, Gabriel S., Fu, Chia-Hsuan, St. Romain, Corey P., Zheng, Yi, Botterill, Justin J., Scharfman, Helen E., Liu, Yin, Chin, Jeannie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268090/ https://www.ncbi.nlm.nih.gov/pubmed/32536852 http://dx.doi.org/10.3389/fnins.2020.00472 |
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