Downregulation of GRK6 in arcuate nucleus promotes chronic visceral hypersensitivity via NF-κB upregulation in adult rats with neonatal maternal deprivation

AIMS: The arcuate nucleus is a vital brain region for coursing of pain command. G protein-coupled kinase 6 (GRK6) accommodates signaling through G protein-coupled receptors. Studies have demonstrated that GRK6 is involved in inflammatory pain and neuropathic pain. The present study was designed to e...

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Detalles Bibliográficos
Autores principales: Li, Xin, Xu, Yu-Cheng, Tian, Yuan-Qin, Zhang, Ping-An, Hu, Shu-Fen, Wang, Lin-Hui, Jiang, Xing-Hong, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268126/
https://www.ncbi.nlm.nih.gov/pubmed/32484026
http://dx.doi.org/10.1177/1744806920930858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268126/
https://www.ncbi.nlm.nih.gov/pubmed/32484026
http://dx.doi.org/10.1177/1744806920930858

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