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Downregulation of GRK6 in arcuate nucleus promotes chronic visceral hypersensitivity via NF-κB upregulation in adult rats with neonatal maternal deprivation
AIMS: The arcuate nucleus is a vital brain region for coursing of pain command. G protein-coupled kinase 6 (GRK6) accommodates signaling through G protein-coupled receptors. Studies have demonstrated that GRK6 is involved in inflammatory pain and neuropathic pain. The present study was designed to e...
Autores principales: | Li, Xin, Xu, Yu-Cheng, Tian, Yuan-Qin, Zhang, Ping-An, Hu, Shu-Fen, Wang, Lin-Hui, Jiang, Xing-Hong, Xu, Guang-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268126/ https://www.ncbi.nlm.nih.gov/pubmed/32484026 http://dx.doi.org/10.1177/1744806920930858 |
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