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Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies

[Image: see text] Studying metal-protein interactions is key for understanding the fate of metallodrugs in biological systems. When a metal complex is not emissive and too weakly bound for mass spectrometry analysis, however, it may become challenging to study such interactions. In this work a synth...

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Detalles Bibliográficos
Autores principales: Busemann, Anja, Araman, Can, Flaspohler, Ingrid, Pratesi, Alessandro, Zhou, Xue-Quan, van Rixel, Vincent H. S., Siegler, Maxime A., Messori, Luigi, van Kasteren, Sander I., Bonnet, Sylvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268191/
https://www.ncbi.nlm.nih.gov/pubmed/32396371
http://dx.doi.org/10.1021/acs.inorgchem.0c00742