Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models

BACKGROUND: Luminal breast cancer (L-BCa) comprises the majority of incurable, distally metastatic breast cancer cases. Estrogen supports growth of L-BCa cells but suppresses invasiveness. Estrogen also induces the progesterone receptor (PR). Invasiveness and metastasis of L-BCa cells is supported b...

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Detalles Bibliográficos
Autores principales: Rosati, Rayna, Oppat, Kailey, Huang, Yanfang, Kim, Seongho, Ratnam, Manohar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268268/
https://www.ncbi.nlm.nih.gov/pubmed/32493230
http://dx.doi.org/10.1186/s12885-020-07002-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268268/
https://www.ncbi.nlm.nih.gov/pubmed/32493230
http://dx.doi.org/10.1186/s12885-020-07002-0

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