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Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma

BACKGROUND: Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6), a key protein involved in synthetizing dihydrotestosterone, is abundant in the liver. Previous studies have suggested a role for dihydrotestosterone in modulating progress of various malignancies, and HSD17B6 dysfunction was associated wi...

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Detalles Bibliográficos
Autores principales: Lv, Lei, Zhao, Yujia, Wei, Qinqin, Zhao, Ye, Yi, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268300/
https://www.ncbi.nlm.nih.gov/pubmed/32514254
http://dx.doi.org/10.1186/s12935-020-01298-5