Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts

BACKGROUND: Previous studies indicate that soyasaponins may reduce inflammation via modulating toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signaling. However, its underlying mechanisms are still not fully understood. METHODS: Lipopolysaccharide (LPS)-challenged inflamed mal...

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Detalles Bibliográficos
Autores principales: Chen, Junbin, Ullah, Hidayat, Zheng, Zhongdaixi, Gu, Xiangfu, Su, Chuhong, Xiao, Lingyu, Wu, Xinglong, Xiong, Fei, Li, Qing, Zha, Longying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268359/
https://www.ncbi.nlm.nih.gov/pubmed/32493316
http://dx.doi.org/10.1186/s12906-020-2864-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268359/
https://www.ncbi.nlm.nih.gov/pubmed/32493316
http://dx.doi.org/10.1186/s12906-020-2864-2

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