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Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer
BACKGROUND: Expression of Oct4 maintains cancer stem cell (CSC)-like properties in lung cancer cells and is correlated with poor prognosis of lung adenocarcinoma. M2-type tumor-associated macrophages (TAMs) promote cancer cell migration and metastasis. Tumor microenvironments promote monocyte differ...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268452/ https://www.ncbi.nlm.nih.gov/pubmed/32487125 http://dx.doi.org/10.1186/s13045-020-00887-1 |