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Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer

BACKGROUND: Expression of Oct4 maintains cancer stem cell (CSC)-like properties in lung cancer cells and is correlated with poor prognosis of lung adenocarcinoma. M2-type tumor-associated macrophages (TAMs) promote cancer cell migration and metastasis. Tumor microenvironments promote monocyte differ...

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Detalles Bibliográficos
Autores principales: Lu, Chia-Sing, Shiau, Ai-Li, Su, Bing-Hua, Hsu, Tsui-Shan, Wang, Chung-Teng, Su, Yu-Chu, Tsai, Ming-Shian, Feng, Yin-Hsun, Tseng, Yau-Lin, Yen, Yi-Ting, Wu, Chao-Liang, Shieh, Gia-Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268452/
https://www.ncbi.nlm.nih.gov/pubmed/32487125
http://dx.doi.org/10.1186/s13045-020-00887-1