Chimeric antigen receptor T cells targeting PD-L1 suppress tumor growth

BACKGROUND: Chimeric antigen receptor T cells (CAR-T cells) therapy has been well recognized for treating B cell-derived malignancy. However, the efficacy of CAR-T cells against solid tumors remains dissatisfactory, partially due to the heterogeneity of solid tumors and T cell exhaustion in tumor mi...

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Detalles Bibliográficos
Autores principales: Qin, Le, Zhao, Ruocong, Chen, Dongmei, Wei, Xinru, Wu, Qiting, Long, Youguo, Jiang, Zhiwu, Li, Yangqiu, Wu, Haipeng, Zhang, Xuchao, Wu, Yilong, Cui, Shuzhong, Wei, Wei, Yao, Huihui, Liu, Zixia, Cao, Su, Yao, Yao, Zhang, Zhenfeng, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268496/
https://www.ncbi.nlm.nih.gov/pubmed/32514352
http://dx.doi.org/10.1186/s40364-020-00198-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268496/
https://www.ncbi.nlm.nih.gov/pubmed/32514352
http://dx.doi.org/10.1186/s40364-020-00198-0

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