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MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

BACKGROUND: The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogeneous tis...

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Detalles Bibliográficos
Autores principales: Friedrich, Stefanie, Barbulescu, Remus, Helleday, Thomas, Sonnhammer, Erik L. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268502/
https://www.ncbi.nlm.nih.gov/pubmed/32487140
http://dx.doi.org/10.1186/s12920-020-00731-y