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MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data
BACKGROUND: The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogeneous tis...
Autores principales: | Friedrich, Stefanie, Barbulescu, Remus, Helleday, Thomas, Sonnhammer, Erik L. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268502/ https://www.ncbi.nlm.nih.gov/pubmed/32487140 http://dx.doi.org/10.1186/s12920-020-00731-y |
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