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Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran

BACKGROUND: Fluoroquinolones are broad-spectrum antibiotics that are recommended, and increasingly important, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Resistance to fluoroquinolones is caused by mutations in the Quinolone Resistance Determining Region (QRDR) of gyrA and gyrB g...

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Detalles Bibliográficos
Autores principales: Sayadi, Mahdieh, Zare, Hosna, Jamedar, Saeed Amel, Hashemy, Seyed Isaac, Meshkat, Zahra, Soleimanpour, Saman, Hoffner, Sven, Ghazvini, Kiarash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268510/
https://www.ncbi.nlm.nih.gov/pubmed/32487030
http://dx.doi.org/10.1186/s12879-020-05112-5