Development of a QPatch-Automated Electrophysiology Assay for Identifying TMEM16A Small-Molecule Inhibitors

The calcium-activated chloride channel, TMEM16A, is involved in airway hydration and bronchoconstriction and is a promising target for respiratory disease. Drug development efforts around channels require an electrophysiology-based assay for identifying inhibitors or activators. TMEM16A has proven t...

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Detalles Bibliográficos
Autores principales: Henckels, Kathryn A., Fong, David, Phillips, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268545/
https://www.ncbi.nlm.nih.gov/pubmed/32319819
http://dx.doi.org/10.1089/adt.2019.962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268545/
https://www.ncbi.nlm.nih.gov/pubmed/32319819
http://dx.doi.org/10.1089/adt.2019.962

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