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Transcription activation of circ-STAT3 induced by Gli2 promotes the progression of hepatoblastoma via acting as a sponge for miR-29a/b/c-3p to upregulate STAT3/Gli2

BACKGROUND: Hepatoblastoma (HB) is a common liver malignancy in children. Our previous study has disclosed the crucial role of STAT3 (signal transducer and activator of transcription 3) in HB. AIM OF THE STUDY: Present study was designed to study the circular RNA (circRNA) STAT3 in HB. METHODS: Gel...

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Detalles Bibliográficos
Autores principales: Liu, Yanfeng, Song, Jianping, Liu, Yu, Zhou, Zhipeng, Wang, Xianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268652/
https://www.ncbi.nlm.nih.gov/pubmed/32493490
http://dx.doi.org/10.1186/s13046-020-01598-8