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An empirical Bayes approach to normalization and differential abundance testing for microbiome data
BACKGROUND: Advances in DNA sequencing have offered researchers an unprecedented opportunity to better study the variety of species living in and on the human body. However, the analysis of microbiome data is complicated by several challenges. First, the sequencing depth may vary by orders of magnit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268703/ https://www.ncbi.nlm.nih.gov/pubmed/32493208 http://dx.doi.org/10.1186/s12859-020-03552-z |