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DAMEfinder: a method to detect differential allele-specific methylation

BACKGROUND: DNA methylation is a highly studied epigenetic signature that is associated with regulation of gene expression, whereby genes with high levels of promoter methylation are generally repressed. Genomic imprinting occurs when one of the parental alleles is methylated, i.e., when there is in...

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Detalles Bibliográficos
Autores principales: Orjuela, Stephany, Machlab, Dania, Menigatti, Mirco, Marra, Giancarlo, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268773/
https://www.ncbi.nlm.nih.gov/pubmed/32487212
http://dx.doi.org/10.1186/s13072-020-00346-8