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Decidual CD8(+)T cells exhibit both residency and tolerance signatures modulated by decidual stromal cells

BACKGROUND: During early pregnancy, tolerance of the semi-allogeneic fetus necessitates comprehensive modifications of the maternal immune system. How decidual CD8(+)T (CD8(+)dT) cells balance maternal tolerance of the fetus with defense from invading pathogens remains undefined. METHODS: We investi...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Huang, Xixi, Xu, Chunfang, Chen, Chunqin, Zhao, Weijie, Li, Dajin, Li, Liping, Wang, Li, Du, Meirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268777/
https://www.ncbi.nlm.nih.gov/pubmed/32487187
http://dx.doi.org/10.1186/s12967-020-02371-3