Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity

BACKGROUND: Consecutive testing of single nucleotide polymorphisms (SNPs) is usually employed to identify genetic variants associated with complex traits. Ideally one should model all covariates in unison, but most existing analysis methods for genome-wide association studies (GWAS) perform only uni...

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Detalles Bibliográficos
Autores principales: Chu, Benjamin B, Keys, Kevin L, German, Christopher A, Zhou, Hua, Zhou, Jin J, Sobel, Eric M, Sinsheimer, Janet S, Lange, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268817/
https://www.ncbi.nlm.nih.gov/pubmed/32491161
http://dx.doi.org/10.1093/gigascience/giaa044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268817/
https://www.ncbi.nlm.nih.gov/pubmed/32491161
http://dx.doi.org/10.1093/gigascience/giaa044

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