Detecting Shared Genetic Architecture Among Multiple Phenotypes by Hierarchical Clustering of Gene-Level Association Statistics

Emerging large-scale biobanks pairing genotype data with phenotype data present new opportunities to prioritize shared genetic associations across multiple phenotypes for molecular validation. Past research, by our group and others, has shown gene-level tests of association produce biologically inte...

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Detalles Bibliográficos
Autores principales: McGuirl, Melissa R., Smith, Samuel Pattillo, Sandstede, Björn, Ramachandran, Sohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268989/
https://www.ncbi.nlm.nih.gov/pubmed/32245788
http://dx.doi.org/10.1534/genetics.120.303096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268989/
https://www.ncbi.nlm.nih.gov/pubmed/32245788
http://dx.doi.org/10.1534/genetics.120.303096

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