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Detecting Shared Genetic Architecture Among Multiple Phenotypes by Hierarchical Clustering of Gene-Level Association Statistics
Emerging large-scale biobanks pairing genotype data with phenotype data present new opportunities to prioritize shared genetic associations across multiple phenotypes for molecular validation. Past research, by our group and others, has shown gene-level tests of association produce biologically inte...
Autores principales: | McGuirl, Melissa R., Smith, Samuel Pattillo, Sandstede, Björn, Ramachandran, Sohini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268989/ https://www.ncbi.nlm.nih.gov/pubmed/32245788 http://dx.doi.org/10.1534/genetics.120.303096 |
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