A composite nanocarrier to inhibit precipitation of the weakly basic drug in the gastrointestinal tract

For weakly basic drugs, the sharp decrease of drug solubility and the following drug precipitation after drugs transferring from the gastric fluid to the intestinal fluid in the gastrointestinal (GI) tract is a main reason for the poor oral bioavailability of drugs. Here, an anticoagulant dabigatran...

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Detalles Bibliográficos
Autores principales: Zheng, Chunli, Li, Yun, Peng, Zhen, He, Xinyi, Tao, Juan, Ge, Liang, Sun, Yixin, Wu, Yunkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269033/
https://www.ncbi.nlm.nih.gov/pubmed/32397763
http://dx.doi.org/10.1080/10717544.2020.1760402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269033/
https://www.ncbi.nlm.nih.gov/pubmed/32397763
http://dx.doi.org/10.1080/10717544.2020.1760402

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