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A composite nanocarrier to inhibit precipitation of the weakly basic drug in the gastrointestinal tract
For weakly basic drugs, the sharp decrease of drug solubility and the following drug precipitation after drugs transferring from the gastric fluid to the intestinal fluid in the gastrointestinal (GI) tract is a main reason for the poor oral bioavailability of drugs. Here, an anticoagulant dabigatran...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269033/ https://www.ncbi.nlm.nih.gov/pubmed/32397763 http://dx.doi.org/10.1080/10717544.2020.1760402 |