Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways

HER2-positive breast cancer accounts for 15–20% in breast cancer and 50% of the metastatic HER2-positive breast cancer patients died of central nervous system progression. The present study investigated the effects of actein (a natural cycloartane triterpene) on cells adhesion, migration, proliferat...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-Xiao, Yue, Grace Gar-Lee, Dong, Jin-Run, Lam, Christopher Wai-Kei, Wong, Chun-Kwok, Qiu, Ming-Hua, Lau, Clara Bik-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269144/
https://www.ncbi.nlm.nih.gov/pubmed/32547952
http://dx.doi.org/10.3389/fonc.2020.00854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269144/
https://www.ncbi.nlm.nih.gov/pubmed/32547952
http://dx.doi.org/10.3389/fonc.2020.00854

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