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Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways

HER2-positive breast cancer accounts for 15–20% in breast cancer and 50% of the metastatic HER2-positive breast cancer patients died of central nervous system progression. The present study investigated the effects of actein (a natural cycloartane triterpene) on cells adhesion, migration, proliferat...

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Detalles Bibliográficos
Autores principales:	Wu, Xiao-Xiao, Yue, Grace Gar-Lee, Dong, Jin-Run, Lam, Christopher Wai-Kei, Wong, Chun-Kwok, Qiu, Ming-Hua, Lau, Clara Bik-San
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269144/ https://www.ncbi.nlm.nih.gov/pubmed/32547952 http://dx.doi.org/10.3389/fonc.2020.00854

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