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Be Cautious with Crystal Structures of Membrane Proteins or Complexes Prepared in Detergents

Membrane proteins are an important class of macromolecules found in all living organisms and many of them serve as important drug targets. In order to understand their biological and biochemical functions and to exploit them for structure-based drug design, high-resolution and accurate structures of...

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Detalles Bibliográficos
Autor principal: Guo, Youzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269168/
https://www.ncbi.nlm.nih.gov/pubmed/32494365
http://dx.doi.org/10.3390/cryst10020086