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Qualitative expression of hypoxia-inducible factor-1α in malignant transformation of oral submucous fibrosis: An immunohistochemical study

BACKGROUND: Oral submucous fibrosis (OSF) is a precancerous condition predominantly seen in people of Asian descent. About 7%–12% of OSF patients develop oral squamous cell carcinoma. Morphological features of OSF, especially fibrosis, suggest a possibility of hypoxic environment in diseased tissues...

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Detalles Bibliográficos
Autores principales: Pereira, Treville, Surve, Ridima, Shetty, Subraj, Gotmare, Swati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269283/
https://www.ncbi.nlm.nih.gov/pubmed/32508457
http://dx.doi.org/10.4103/jomfp.JOMFP_234_19