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Clofazimine enhances the efficacy of BCG revaccination via stem cell-like memory T cells

Tuberculosis (TB) is one of the deadliest diseases, claiming ~2 million deaths annually worldwide. The majority of people in TB endemic regions are vaccinated with Bacillus Calmette Guerin (BCG), which is the only usable vaccine available. BCG is efficacious against meningeal and disseminated TB in...

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Detalles Bibliográficos
Autores principales: Ahmad, Shaheer, Bhattacharya, Debapriya, Gupta, Neeta, Rawat, Varsha, Tousif, Sultan, Van Kaer, Luc, Das, Gobardhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269335/
https://www.ncbi.nlm.nih.gov/pubmed/32437421
http://dx.doi.org/10.1371/journal.ppat.1008356