Cargando…

Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages

Coronaviruses (CoVs) encode multiple interferon (IFN) antagonists that modulate the host response to virus replication. Here, we evaluated the host transcriptional response to infection with murine coronaviruses encoding independent mutations in one of two different viral antagonists, the deubiquiti...

Descripción completa

Detalles Bibliográficos
Autores principales: Volk, Aaron, Hackbart, Matthew, Deng, Xufang, Cruz-Pulido, Yazmin, O’Brien, Amornrat, Baker, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269425/
https://www.ncbi.nlm.nih.gov/pubmed/32188729
http://dx.doi.org/10.1128/JVI.00178-20