Cargando…
Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes
Retroviral replication proceeds through obligate integration of the viral DNA into the host genome. In particular, for the HIV-1 genome to enter the nucleus, it must be led through the nuclear pore complex (NPC). During the HIV-1 cytoplasmic journey, the viral core acts as a shell to protect the vir...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269431/ https://www.ncbi.nlm.nih.gov/pubmed/32238582 http://dx.doi.org/10.1128/JVI.00135-20 |