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Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes

Retroviral replication proceeds through obligate integration of the viral DNA into the host genome. In particular, for the HIV-1 genome to enter the nucleus, it must be led through the nuclear pore complex (NPC). During the HIV-1 cytoplasmic journey, the viral core acts as a shell to protect the vir...

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Detalles Bibliográficos
Autores principales: Blanco-Rodriguez, Guillermo, Gazi, Anastasia, Monel, Blandine, Frabetti, Stella, Scoca, Viviana, Mueller, Florian, Schwartz, Olivier, Krijnse-Locker, Jacomine, Charneau, Pierre, Di Nunzio, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269431/
https://www.ncbi.nlm.nih.gov/pubmed/32238582
http://dx.doi.org/10.1128/JVI.00135-20