Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases

Most of the current antibody-drug conjugates (ADCs) in clinic are heterogeneous mixtures. To produce homogeneous ADCs, established procedures often require multiple steps or long reaction times. The introduced mutations or foreign sequences may cause high immunogenicity. Here, we explore a new conce...

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Detalles Bibliográficos
Autores principales: Dai, Zhefu, Zhang, Xiao-Nan, Nasertorabi, Fariborz, Cheng, Qinqin, Li, Jiawei, Katz, Benjamin B., Smbatyan, Goar, Pei, Hua, Louie, Stan G., Lenz, Heinz-Josef, Stevens, Raymond C., Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269645/
https://www.ncbi.nlm.nih.gov/pubmed/32537509
http://dx.doi.org/10.1126/sciadv.aba6752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269645/
https://www.ncbi.nlm.nih.gov/pubmed/32537509
http://dx.doi.org/10.1126/sciadv.aba6752

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