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A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins

Health care authorities are calling for new antibacterial therapies to cope with the global emergence of antibiotic-resistant bacteria. Bacteriophage-encoded lysins are a unique class of antibacterials with promising (pre)clinical progress. Custom engineering of lysins allows for the creation of var...

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Detalles Bibliográficos
Autores principales: Gerstmans, H., Grimon, D., Gutiérrez, D., Lood, C., Rodríguez, A., van Noort, V., Lammertyn, J., Lavigne, R., Briers, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269649/
https://www.ncbi.nlm.nih.gov/pubmed/32537492
http://dx.doi.org/10.1126/sciadv.aaz1136