Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin

Studies have suggested that amyloid precursor protein (APP) regulates synaptic homeostasis, but the evidence has not been consistent. In particular, signaling pathways controlling APP transport to the synapse in axons and dendrites remain to be identified. Having previously shown that Huntingtin (HT...

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Detalles Bibliográficos
Autores principales: Bruyère, Julie, Abada, Yah-Se, Vitet, Hélène, Fontaine, Gaëlle, Deloulme, Jean-Christophe, Cès, Aurélia, Denarier, Eric, Pernet-Gallay, Karin, Andrieux, Annie, Humbert, Sandrine, Potier, Marie-Claude, Delatour, Benoît, Saudou, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269668/
https://www.ncbi.nlm.nih.gov/pubmed/32452382
http://dx.doi.org/10.7554/eLife.56371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269668/
https://www.ncbi.nlm.nih.gov/pubmed/32452382
http://dx.doi.org/10.7554/eLife.56371

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