STK38 promotes ATM activation by acting as a reader of histone H4 ufmylation

The ATM (ataxia-telangiectasia mutated) kinase is rapidly activated following DNA damage and phosphorylates its downstream targets to launch DDR signaling. Recently, we and others showed that UFM1 signaling promotes ATM activation. We further discovered that monoufmylation of histone H4 at Lys(31) b...

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Detalles Bibliográficos
Autores principales: Qin, Bo, Yu, Jia, Nowsheen, Somaira, Zhao, Fei, Wang, Liewei, Lou, Zhenkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269669/
https://www.ncbi.nlm.nih.gov/pubmed/32537488
http://dx.doi.org/10.1126/sciadv.aax8214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269669/
https://www.ncbi.nlm.nih.gov/pubmed/32537488
http://dx.doi.org/10.1126/sciadv.aax8214

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