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Stochastic bond dynamics facilitates alignment of malaria parasite at erythrocyte membrane upon invasion

Malaria parasites invade healthy red blood cells (RBCs) during the blood stage of the disease. Even though parasites initially adhere to RBCs with a random orientation, they need to align their apex toward the membrane in order to start the invasion process. Using hydrodynamic simulations of a RBC a...

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Detalles Bibliográficos
Autores principales: Hillringhaus, Sebastian, Dasanna, Anil K, Gompper, Gerhard, Fedosov, Dmitry A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269671/
https://www.ncbi.nlm.nih.gov/pubmed/32420874
http://dx.doi.org/10.7554/eLife.56500