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Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma

MiRNAlet-7a is associated with the tumorigenesis of laryngeal squamous cell carcinoma (LSCC). Our study was designed to infer whether let-7a targets high-mobility AT-hook 2 (HMGA2) and suppresses laryngeal carcinoma cell proliferation, invasion, and migration. The expression levels of let-7a and HMG...

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Detalles Bibliográficos
Autores principales: Ma, Li-Juan, Wu, Jun, Zhou, En, Yin, Juan, Xiao, Xu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269914/
https://www.ncbi.nlm.nih.gov/pubmed/32432318
http://dx.doi.org/10.1042/BSR20193788