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Wnt16 Overexpression in Osteoblasts Increases the Subchondral Bone Mass but has no Impact on Osteoarthritis in Young Adult Female Mice

Epidemiological studies have shown that high bone mineral density (BMD) is associated with an increased risk of osteoarthritis (OA), but the causality of this relationship remains unclear. Both bone mass and OA have been associated with the WNT signaling pathway in genetic studies, there is thus an...

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Detalles Bibliográficos
Autores principales: Törnqvist, Anna E., Grahnemo, Louise, Nilsson, Karin H., Funck-Brentano, Thomas, Ohlsson, Claes, Movérare-Skrtic, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270053/
https://www.ncbi.nlm.nih.gov/pubmed/32140758
http://dx.doi.org/10.1007/s00223-020-00682-7