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Methylation of the Phospholipase A2 Receptor 1 Promoter Region in Childhood B Cell Acute Lymphoblastic Leukaemia

Acute lymphoblastic leukaemia (ALL) is the most common form of paediatric cancer and epigenetic aberrations are determinants of leukaemogenesis. The aim of this study was to investigate the methylation degree of a distinct phospholipase A2 receptor 1 (PLA2R1) promoter region in paediatric ALL patien...

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Detalles Bibliográficos
Autores principales: Friedemann, Markus, Gutewort, Katharina, Thiem, Dana, Nacke, Brit, Jandeck, Carsten, Lange, Björn Sönke, Sukocheva, Olga, Suttorp, Meinolf, Menschikowski, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270080/
https://www.ncbi.nlm.nih.gov/pubmed/32493972
http://dx.doi.org/10.1038/s41598-020-65825-0