Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

The transcription factor JUN is highly expressed in pulmonary fibrosis. Its induction in mice drives lung fibrosis, which is abrogated by administration of anti-CD47. Here, we use high-dimensional mass cytometry to profile protein expression and secretome of cells from patients with pulmonary fibros...

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Detalles Bibliográficos
Autores principales: Cui, Lu, Chen, Shih-Yu, Lerbs, Tristan, Lee, Jin-Wook, Domizi, Pablo, Gordon, Sydney, Kim, Yong-hun, Nolan, Garry, Betancur, Paola, Wernig, Gerlinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270081/
https://www.ncbi.nlm.nih.gov/pubmed/32493933
http://dx.doi.org/10.1038/s41467-020-16466-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270081/
https://www.ncbi.nlm.nih.gov/pubmed/32493933
http://dx.doi.org/10.1038/s41467-020-16466-4

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