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Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products

The discovery and development of multistage antimalarial drugs targeting intra-erythrocytic asexual and sexual Plasmodium falciparum parasites is of utmost importance to achieve the ambitious goal of malaria elimination. Here, we report the validation of naphthylisoquinoline (NIQ) alkaloids and thei...

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Detalles Bibliográficos
Autores principales: Moyo, Phanankosi, Shamburger, William, van der Watt, Mariëtte E., Reader, Janette, de Sousa, Ana Carolina C., Egan, Timothy J., Maharaj, Vinesh J., Bringmann, Gerhard, Birkholtz, Lyn-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270141/
https://www.ncbi.nlm.nih.gov/pubmed/32505117
http://dx.doi.org/10.1016/j.ijpddr.2020.05.003